By Jeff Levine - October 10, 2008 - AARP Bulletin Today
Since the flu is nothing to sneeze at, experts are making their annual plea for people 50-plus and other at-risk groups to get their shots.
Public health officials say a new vaccine from five different manufacturers has been shipped to clinics and doctors’ offices around the country. There should be enough to go around. According to Julie Gerberding, M.D., director of the U.S. Centers for Disease Control and Prevention (CDC), between 143 million and 146 million doses are available, ruling out any shortage like the one that occurred in 2004, when the vaccine supply was cut in half.
Influenza—the fancy word for the flu—is an infectious respiratory disease, caused by a virus, that can be really dangerous to at-risk groups, including the older people, infants and people with chronic diseases. Flu and bacterial pneumonia—a common complication of flu—each year send 200,000 people to hospitals in the United States and cause on average 36,000 deaths.
Immunizations usually help individuals avoid the flu, but public health officials are concerned that this season, people may be reluctant to be inoculated. That’s because last year’s circulating virus strains did not match up with the vaccine, so more people came down with the flu.
Vaccine formulations are determined each year by scientists who look at the dominant strains in the Southern Hemisphere. In February they recommend the three viruses that are most likely to strike the United States in the next flu season. Usually one or two strains are used from the previous year’s vaccine. But this year’s formulation is “unprecedented,” says Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), because the vaccine has been manufactured with three new strains.
In 16 of the last 19 years, the vaccine has been a good match with prevailing viruses, says Joe Bresee, M.D., head of the CDC’s flu prevention effort. Normally, a shot works for 70 to 90 percent of those immunized, he says, but last year only 44 percent were protected.
Betty, an 81-year-old Fairfax, Va., resident who doesn’t wish to be identified, was one person for whom last year’s vaccine failed. She got her regular flu shot in October 2007 and thought she was protected. A month later she became severely ill.
“One day out of the blue, I just got a real high temperature and almost blacked out and started sweating,” Betty says. She went to the emergency room, where she was diagnosed with the flu and spent four days in the isolation ward. Despite her experience, she says she’ll get another flu shot this fall.
Betty’s gerontologist, Joanne Crantz, M.D., was also disappointed with last year’s vaccine. “It’s always disconcerting when you give someone a shot that you think is going to be protective, and it’s not,” she says. She saw 20 cases of flu last year in patients, some of whom had been vaccinated.
The vaccine has come under scrutiny from other sources as well. In fact, some doctors don’t think it prevents disease in the older population. They point to a study published in the British medical journal the Lancet on Aug. 2, which found that the vaccine didn’t lower the risk of pneumonia. Researchers at the Group Health Center for Health Studies in Seattle found that older people who are the most likely to get a flu shot are generally healthy and the least likely to get pneumonia, while those too weak or frail to get to the doctor’s office for a vaccination are the most vulnerable. Factoring in the variations in health status, the vaccine appeared to make little difference in pneumonia risk. The findings were based on a review of thousands of medical charts of older members of a Seattle HMO.
Still, many health experts remained unconvinced. Crantz, despite her disappointment over the vaccine’s effectiveness last year, says she doesn’t agree with the study’s conclusions. “Some very hardy people get the flu,” she says. And even the study’s lead author, Michael L. Jackson, said in a press report that he “still wants my grandmother to keep getting the flu vaccine ... even if it might lower the risk of pneumonia and death only slightly.”
“People may question whether the vaccine is effective,” adds the CDC’s Bresee, “but they need to remember it’s still the best protection we have year in and year out.”
Walter Orenstein, M.D., the former head of the CDC’s national immunization effort, says flu “has emerged as a health security issue because of its huge medical and economic toll.” Despite this, he says, warnings about the flu are too often ignored.
A new CDC report shows that in 2006, 72 percent of those older than 65 were vaccinated, but only 42 percent of individuals ages 50 to 64 and 35 percent of 18- to 49-year-olds were immunized. Just 42 percent of health workers got the shots. And a new consumer survey commissioned by the National Foundation for Infectious Diseases (NFID) shows that four in 10 patients say they’ve never even talked with their doctors about being vaccinated.
What’s likely to get more people to roll up their sleeves is a longer-lasting vaccine that confers immunity from year to year. “I think that’s the ultimate endgame and endpoint, but we’re not there yet, obviously,” says Fauci. Currently, NIAID is spending about $94 million on developing vaccines for different types of flu, up from just $3.6 million in 2000, before the 9/11 attacks, the anthrax scare and worries about avian flu.
In the meantime, AARP board member Cora Christian, M.D., said at an NFID press briefing, “Get the flu shot—it’s a powerful preventive weapon.”
Who should get immunized?
• People age 50 and older
• Nursing home residents
• Health care workers
• People with chronic diseases that weaken their immune systems
• People who are in contact with those at high risk for flu
• Children and teens, from six months to 18 years old
• Pregnant women
Types of vaccines
• Traditional flu shot consisting of a “killed” virus for healthy people older than six months
• Nose spray consisting of a weakened live virus for healthy people ages 2 to 49 years (but not pregnant women)
• A one-time vaccination against bacterial pneumonia, a common complication of flu, for those 65 and older and nursing home residents
Clinics and Costs
• Flu shots generally cost between $15 and $30, but check hospitals, senior centers, pharmacies and public clinics in your community for free or low-cost shots.
• Some polling places are offering flu shots on Election Day through the Vote and Vax program.
• Medicare pays for the total cost of flu and pneumonia vaccinations, and so do many private health plans.
Helpful Websites:
• AARP offers tips on protecting yourself from the flu.
• The Centers for Disease Control and Prevention offers information on everything from prevention to flu symptoms to treatment.
• The American Lung Association provides information on pneumonia associated with the flu and a site to help you find a flu clinic in your area.
• Medicare’s site focuses on flu and people 65-plus.
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